Health

Authors Hummer, Joanna; Birngruber, Thomas; Sinner, Frank; Page, Leanne; Toner, Frank; Roper, Clive S.; Moore, David J.; Baker, Mark B.; Boncheva Bettex, Mila

Health

2022

Digital algorithm-guided insulin therapy in home healthcare for elderly persons with type 2 diabetes: A proof-of-concept study

Authors Kopanz, Julia; Mader, Julia K.; Donsa, Klaus; Libiseller, Angela; Aberer, Felix; Pandis, Marlene; Reinisch-Gratzer, Johanna; Ambrosch, Gisela C.; Lackner, Bettina; Truskaller, Thomas; Sinner, Frank Michael; Pieber, Thomas Rudolf; Lichtenegger, Katharina M.

Health

2021

Electronic Diabetes Management System Replaces Paper Insulin Chart: Improved Quality in Diabetes Inpatient Care Processes Due to Digitalization

Authors Kopanz, Julia; Lichtenegger, Katharina M.; Koenig, Constanze; Libiseller, Angela; Mader, Julia K.; Donsa, Klaus; Truskaller, Thomas; Bauer, Norbert; Hahn, Brigitte; Sendlhofer, Gerald; Beck, Peter; Höll, Bernhard; Sinner, Frank; Feichtner, Franz; Pieber, Thomas R.

Health

2021

Dermal sampling techniques with focus on dermal Open Flow Microperfusion

Authors Birngruber, Thomas; Boulgaropoulos, Beate; Sinner, Frank

Health

2021

Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging

Authors Handler, Anne Mette; Eirefelt, Stefan; Lambert, Maja; Johansson, Fredrik; Hollesen Schefe, Line; Østergaard Knudsen, Nina; Bodenlenz, Manfred; Birngruber, Thomas; Sinner, Frank; Huss Erikson, André; Pommergaard Pedersen, Gitte; Janfelt, Christian; Troensegaard Nielsen, Kim

Health

2021

Dietary spermidine improves cognitive function

Authors Schroeder, Sabrina; Hofer, Sebastian J.; Zimmermann, Andreas; Pechlaner, Raimund; Dammbrueck, Christopher; Pendl, Tobias; Marcello, G. Mark; Pogatschnigg, Viktoria; Bergmann, Martina; Müller, Melanie; Gschiel, Verena; Ristic, Selena; Tadic, Jelena; Iwata, Keiko; Richter, Gesa; Farzi, Aitak; Üçal, Muammer; Schäfer, Ute; Poglitsch, Michael; Royer, Philipp; Mekis, Ronald; Agreiter, Marlene; Tölle, Regine C.; Sótonyi, Péter; Willeit, Johann; Mairhofer, Barbara; Niederkofler, Helga; Pallhuber, Irmgard; Rungger, Gregorio; Tilg, Herbert; Defrancesco, Michaela; Marksteiner, Josef; Sinner, Frank; Magnes, Christoph; Pieber, Thomas R.; Holzer, Peter; Kroemer, Guido; Carmona-Gutierrez, Didac; Scorrano, Luca; Dengjel, Jörn; Madl, Tobias; Sedej, Simon; Sigrist, Stephan J.; Rácz, Bence; Kiechl, Stefan; Eisenberg, Tobias; Madeo, Frank

Health

2020

Variability of Skin Pharmacokinetic Data: Insights from a Topical Bioequivalence Study Using Dermal Open Flow Microperfusion

Authors Bodenlenz, Manfred; Augustin, Thomas; Birngruber, Thomas; Tiffner, Katrin Irene; Boulgaropoulos, Beate; Schwingenschuh, Simon; Raney, Sam G.; Rantou, Elena; Sinner, Frank

Health

2020

OFM recirculation and OFM suction: Advanced in-vivo open flow microperfusion methods for direct and absolute quantification of albumin in interstitial fluid

Authors Hummer, Joanna; Schwingenschuh, Simon; Raml, Reingard; Boulgaropoulos, Beate; Schwagerle, Gerd; Augustin, Thomas; Sinner, Frank; Birngruber, Thomas

Health

2020

Evaluating Dermal Pharmacokinetics and Pharmacodymanic Effect of Soft Topical PDE4 Inhibitors: Open Flow Microperfusion and Skin Biopsies

Authors Eirefelt, Stefan; Hummer, Joanna; Basse, Line Hollesen; Bertelsen, Malene; Johansson, Fredrik; Birngruber, Thomas; Sinner, Frank; Larsen, Jens; Nielsen, Simon Feldbæk; Lambert, Maja

Health

2019

Comparison of cerebral Open Flow Microperfusion and Microdialysis when sampling small lipophilic and small hydrophilic substances

Authors Altendorfer-Kroath, Thomas; Schimek, Denise; Eberl, Anita; Rauter, Günther; Ratzer, Maria; Raml, Reingard; Sinner, Frank; Birngruber, Thomas

Health

2019

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

Authors Carmona-Gutierrez, Didac; Zimmermann, Andreas; Kainz, Katharina; Pietrocola, Federico; Chen, Guo; Maglioni, Silvia; Schiavi, Alfonso; Nah, Jihoon; Mertel, Sara; Beuschel, Christine B.; Castoldi, Francesca; Sica, Valentina; Trausinger, Gert; Raml, Reingard; Sommer, Cornelia; Schroeder, Sabrina; Hofer, Sebastian J.; Bauer, Maria A.; Pendl, Tobias; Tadic, Jelena; Dammbrueck, Christopher; Hu, Zehan; Ruckenstuhl, Christoph; Eisenberg, Tobias; Durand, Sylvere; Bossut, Noélie; Aprahamian, Fanny; Abdellatif, Mahmoud; Sedej, Simon; Enot, David P.; Wolinski, Heimo; Dengjel, Jörn; Kepp, Oliver; Magnes, Christoph; Sinner, Frank M.; Pieber, Thomas R.; Sadoshima, Junichi; Ventura, Natascia; Sigrist, Stephan J.; Kroemer, Guido; Madeo, Frank

Health

2019

LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation

Authors Pipper, Cornelia; Bordag, Natalie; Reiter, Bernadette; Economides, Kyriakos; Florian, Peter; Birngruber, Thomas; Sinner, Frank; Bodenlenz, Manfred; Eberl, Anita

Health

2019

Insulin distribution in human adipose tissue via a novel insulin infusion catheter

Authors Altendorfer‐Kroath, Thomas; Schwingenschuh, Simon; Schondorff-Kruse, Pernelle; Heschel, Matthias; Sinner, Frank; Birngruber, Thomas

Health

2019

Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans

Authors Stekovic, Slaven; Hofer, Sebastian J.; Tripolt, Norbert; Aon, Miguel A.; Royer, Philipp; Pein, Lukas; Stadler, Julia T.; Pendl, Tobias; Prietl, Barbara; Url, Jasmin; Schroeder, Sabrina; Tadic, Jelena; Eisenberg, Tobias; Magnes, Christoph; Stumpe, Michael; Zuegner, Elmar; Bordag, Natalie; Riedl, Regina; Schmidt, Albrecht; Kolesnik, Ewald; Verheyen, Nicolas; Springer, Anna; Madl, Tobias; Sinner, Frank; de Cabo, Rafael; Kroemer, Guido; Obermayer-Pietsch, Barbara; Dengjel, Jöm; Sourij, Harald; Pieber, Thomas R.; Madeo, Frank

Health

2018

A comprehensive approach to qualify and validate the essential parameters of an in vitro release test (IVRT) method for acyclovir cream, 5%

Authors Tiffner, Katrin Irene; Kanfer, Isadore; Augustin, Thomas; Raml, Reingard; Raney, Sam G.; Sinner, Frank M.

Health

2018

Quantification of acyclovir in dermal interstitial fluid and human serum by ultra-high-performance liquid-high-resolution tandem mass spectrometry for topical bioequivalence evaluation

Authors Schimek, Denise; Raml, Reingard; Francesconi, Kevin A.; Bodenlenz, Manfred; Sinner, Frank

Health

2018

Development of a Protocol for Automated Glucose Measurement Transmission Used in Clinical Decision Support Systems Based on the Continua Design Guidelines

Authors Meyer, Markus; Donsa, Klaus; Truskaller, Thomas; Frohner, Matthias; Pohn, B; Felfernig, A; Sinner, F; Pieber, Thomas R

Health

2018

Intelligent NFC potassium measurement strip with hemolysis check in capillary blood

Authors Kollegger, Carolin; Greiner, Philipp; Siegl, Inge; Steffan, Christoph; Wiessflecker, Martin; Pekec, Bruna; Hajnsek, Martin; Sinner, Frank; Holweg, Gerald; Deutschmann, Bernd

Health

2017

Assessment of skin permeability to topically applied drugs by skin impedance and admittance.

Authors Schwingenschuh, Simon; Scharfetter, Hermann; Martinsen, Orjan Grottem; Boulgaropoulos, Beate; Augustin, Thomas; Tiffner, Katrin Irene; Dragatin, Christian; Raml, Reingard; Hoefferer, Christian; Prandl, Eva-Christina; Sinner, Frank M.; Hajnsek, Martin

Health

2017

Quantification of Basal Insulin Peglispro and Human Insulin in Adipose Tissue Interstitial Fluid by Open-Flow Microperfusion

Authors Tiffner, Katrin Irene; Boulgaropoulos, Beate; Höfferer, Christian; Birngruber, Thomas; Porksen, Niels; Linnebjerg, Helle; Garhyan, Parag; Lam, Eric Chen Quin; Knadler, Mary Pat; Pieber, Thomas R; Sinner, Frank M.

Health

2017

Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence

Authors Bodenlenz, Manfred; Tiffner, Katrin Irene; Raml, Reingard; Augustin, Thomas; Dragatin, Christian; Birngruber, Thomas; Schimek, Denise; Schwagerle, Gerd; Pieber, Thomas R.; Raney, Sam G.; Kanfer, Isadore; Sinner, Frank

Health

2017

β-Defensin 2 is a responsive biomarker of IL-17A–driven skin pathology in patients with psoriasis

Authors Kolbinger, Frank; Loesche, Christian; Valentin, Marie-Anne; Jiang, Xiaoyu; Cheng, Yi; Jarvis, Philip; Peters, Thomas; Calonder, Claudio; Bruin, Gerard; Polus, Florine; Aigner, B; Lee, David M.; Bodenlenz, Manfred; Sinner, Frank; Pieber, Thomas R; Patel, Dhavalkumar D.

Health

2017

First application of a transcutaneous optical single-port glucose monitoring device in patients with type 1 diabetes mellitus.

Authors Rumpler, M; Mader, J K; Fischer, J P; Thar, R; Granger, J M; Deliane, F; Klimant, I; Aberer, F; Sinner, Frank M.; Pieber, Thomas R; Hajnsek, M

Health

2017

An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood-brain barrier uptake

Authors Bode, Gerard H; Coué, Grégory; Freese, Christian; Pickl, Karin E; Sanchez-Purrà, Maria; Albaiges, Berta; Borrós, Salvador; van Winden, Ewoud C; Tziveleka, Leto-Aikaterini; Sideratou, Zili; Engbersen, Johan F; Singh, Smriti; Albrecht, Krystyna; Groll, Jürgen; Möller, Martin; Pötgens, Andy J G; Schmitz, Christoph; Fröhlich, Eleonore Esther E.; Grandfils, Christian; Sinner, Frank M; Kirkpatrick, C James; Steinbusch, Harry W M; Frank, Hans-Georg; Unger, Ronald E; Martinez-Martinez, Pilar

Health

2016

An Untargeted Metabolomics Approach to Characterize Short-Term and Long-Term Metabolic Changes after Bariatric Surgery

Authors Narath, Sophie H.; Mautner, Selma I.; Svehlikova, Eva; Schultes, Bernd; Pieber, Thomas R.; Sinner, Frank M.; Gander, Edgar; Libiseller, Gunnar; Schimek, Michael G.; Sourij, Harald; Magnes, Christoph

Health

2016

Secukinumab distributes into dermal interstitial fluid of psoriasis patients as demonstrated by open flow microperfusion.

Authors Dragatin, Christian; Polus, Florine; Bodenlenz, Manfred; Calonder, Claudio; Aigner, Birgit; Tiffner, Katrin Irene; Mader, Julia Katharina; Ratzer, Maria; Woessner, Ralph; Pieber, Thomas R; Cheng, Yi; Loesche, Christian; Sinner, Frank M.; Bruin, Gerard

Health

2016

Kinetics of Clobetasol-17-Propionate in Psoriatic Lesional and Non-Lesional Skin Assessed by Dermal Open Flow Microperfusion with Time and Space Resolution

Authors Bodenlenz, Manfred; Dragatin, Christian; Liebenberger, Lisa; Tschapeller, Bernd; Boulgaropoulos, Beate; Augustin, Thomas; Raml, Reingard; Gatschelhofer, Christina; Wagner, Nathalie; Benkali, Khaled; Rony, Francois; Pieber, Thomas; Sinner, Frank

Health

2016

Determination of (2)H-enrichment of rat brain interstitial fluid and rat plasma by headspace-gas-chromatography - quadrupole-mass-spectrometry

Authors Eberl, A; Altendorfer‐Kroath, Thomas; Kollmann, D; Birngruber, Thomas; Sinner, F; Raml, R; Magnes, Christoph

Health

2016

Cerebral open flow microperfusion (cOFM) an innovative interface to brain tissue

Authors Birngruber, Thomas; Sinner, Frank

Health

2016

Interleukin-17A blockade with secukinumab results in decreased neutrophil infiltration in psoriasis: minimally-invasive measurement by tape stripping

Authors Loesche, Christian; Kolbinger, Frank; Valentin, Marie-anne; Jarvis, Philip; Ceci, Melanie; Wieczorek, Grazyna; Khokhlovich, Edward; Koroleva, Irina; Bruin, Gerard; Sinner, Frank M.; Aigner, B; Patel, Dhavalkumar D

Health

2015

IPO: a tool for automated optimization of XCMS parameters

Authors Libiseller, Gunnar; Dvorzak, Michaela; Kleb, Ulrike; Gander, Edgar; Eisenberg, Tobias; Madeo, Frank; Neumann, Steffen; Trausinger, Gert; Sinner, Frank; Pieber, Thomas; Magnes, Christoph

Health

2015

Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin

Authors Braun, Ralf J.; Sommer, Cornelia; Leibiger, Christine; Gentier, Romina J.G.; Dumit, Verónica I.; Paduch, Katrin; Eisenberg, Tobias; Habernig, Lukas; Trausinger, Gert; Magnes, Christoph; Pieber, Thomas; Sinner, Frank; Dengjel, Jörn; van Leeuwen, Fred W.; Kroemer, Guido; Madeo, Frank

Health

2015

Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast

Authors Braun, Ralf J.; Sommer, Cornelia; Leibiger, Christine; Gentier, Romina; Dumit, Veronica; Paduch, Katrin; Eisenberg, Tobias; Habernig, Lukas; Trausinger, Gert; Magnes, Christoph; Pieber, Thomas R; Sinner, Frank M; Dengjel, Jörn; van Leeuwen, Fred; Kroemer, Guido; Madeo, Frank

Health

2015

Open flow microperfusion: pharmacokinetics of human insulin and insulin detemir in the interstitial fluid of subcutaneous adipose tissue.

Authors Höfferer, C; Tutkur, D; Fledelius, C; Brand, C L; Alsted, T J; Damgaard, J; Nishimura, E; Jeppesen, C B; Mautner, S. I.; Pieber, Thomas R; Sinner, Frank M.

Health

2015

An electrochemical sensor for fast detection of wound infection based on myeloperoxidase activity

Authors Hajnsek, Martin; Schiffer, Doris; Harrich, Daniel; Koller, Daniel; Verient, Vanessa; Palen, Job V.D. D; Heinzle, Andrea; Binder, Barbara; Sigl, Eva; Sinner, Frank M.; Guebitz, Georg M.

Health

2014

Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx,®/Doxil®—A Cerebral Open Flow Microperfusion Pilot Study

Authors Birngruber, Thomas; Raml, Reingard; Gladdines, Werner; Gatschelhofer, Christina; Gander, Edgar; Ghosh, Arijit; Kroath, Thomas; Gaillard, Pieter J; Pieber, Thomas R; Sinner, Frank

Health

2014

Assessment of blood-brain barrier function and the neuroinflammatory response in the rat brain by using cerebral open flow microperfusion (cOFM).

Authors Ghosh, Arijit; Birngruber, Thomas; Sattler, Wolfgang; Kroath, Thomas; Ratzer, Maria; Sinner, Frank M.; Pieber, Thomas R

Health

2014

Long-Term Implanted cOFM Probe Causes Minimal Tissue Reaction in the Brain

Authors Birngruber, Thomas; Ghosh, Arijit; Hochmeister, Sonja; Asslaber, Martin; Kroath, Thomas; Pieber, Thomas R.; Sinner, Frank

Health

2013

Clinical applicability of dOFM devices for dermal sampling.

Authors Bodenlenz, Manfred; Aigner, B; Dragatin, C; Liebenberger, L; Zahiragic, S; Höfferer, C; Birngruber, Thomas; Priedl, J; Feichtner, F; Schaupp, L; Korsatko, S; Ratzer, M; Magnes, Christoph; Pieber, Thomas R; Sinner, F

Health

2013

Spermidine promotes mating and fertilization efficiency in model organisms

Authors Bauer, Maria Anna; Carmona-Gutiérrez, Didac; Ruckenstuhl, Christoph; Reisenbichler, Angela; Megalou, Evgenia V.; Eisenberg, Tobias; Magnes, Christoph; Jungwirth, Helmut; Sinner, Frank M; Pieber, Thomas R; Fröhlich, Kai Uwe; Kroemer, Guido; Tavernarakis, Nektarios; Madeo, Frank

Health

2013

Design and physicochemical characterization of poly(amidoamine) nanoparticles and the toxicological evaluation in human endothelial cells: applications to peptide delivery to the brain

Authors Coué, Grégory; Freese, Christian; Unger, Ronald E; Kirkpatrick, C James; Pickl, Karin E; Sinner, Frank M; Engbersen, Johan F J

Health

2013

Enhanced absorption of insulin aspart as the result of a dispersed injection strategy tested in a randomized trial in type 1 diabetic patients

Authors Mader, Julia K; Birngruber, Thomas; Korsatko, Stefan; Deller, Sigrid; Köhler, Gerd; Boysen, Susanne; Augustin, Thomas; Mautner, Selma; Sinner, Frank; Pieber, Thomas R; AP@home Consortium

Health

2013

Cerebral open flow microperfusion: a new in vivo technique for continuous measurement of substance transport across the intact blood-brain barrier.

Authors Birngruber, Thomas; Ghosh, Arijit; Perez-Yarza, Veronica; Kroath, Thomas; Ratzer, Maria; Pieber, Thomas R; Sinner, Frank M.

Health, Materials

2013

Design and evaluation of a microfluidic-based whole blood pre-treatment module to detect folic acid.

Authors Rumpler, M.; Suppan, M.; Hajnsek, M.; Satzinger, V.; Köstler, St; Sinner, F.

Health

2012

Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling

Authors Bodenlenz, Manfred; Höfferer, Christian; Magnes, Christoph; Schaller-Ammann, Roland; Schaupp, Lukas; Feichtner, Franz; Ratzer, Maria; Pickl, Karin; Sinner, Frank; Wutte, Andrea; Korsatko, Stefan; Köhler, Gerd; Legat, Franz J.; Benfeldt, Eva M.; Wright, Andrew M.; Neddermann, Daniel; Jung, Thomas; Pieber, Thomas R

Health

2012

Remodeling of lipid droplets during lipolysis and growth in adipocytes

Authors Paar, Margret; Jüngst, Christian; Steiner, Noemi A.; Magnes, Christoph; Sinner, Frank; Kolb, Dagmar; Lass, Achim; Zimmermann, Robert; Zumbusch, Andreas; Kohlwein, Sepp D.; Wolinski, Heimo

Health

2012

Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury

Authors Moustafa, Tarek; Fickert, Peter; Magnes, Christoph; Guelly, Christian; Thueringer, Andrea; Frank, Sasa; Kratky, Dagmar; Sattler, Wolfgang; Reicher, Helga; Sinner, Frank; Gumhold, Judith; Silbert, Dagmar; Fauler, Günter; Höfler, Gerald; Lass, Achim; Zechner, Rudolf; Trauner, Michael

Health

2012

Monolithic precolumns as efficient tools for guiding the design of nanoparticulate drug-delivery formulations

Authors Gatschelhofer, Christina; Prasch, Agnes; Buchmeiser, Michael R; Zimmer, Andreas; Wernig, Karin; Griesbacher, Martin; Pieber, Thomas R; Sinner, Frank M

Health

2012

Open Flow Microperfusion: An Alternative Method to Microdialysis?

Authors Pieber, Thomas R; Birngruber, Thomas; Bodenlenz, Manfred; Höfferer, Christian; Mautner, S. I.; Tiffner, Katrin Irene; Sinner, Frank M.

Health

2012

Comparison of Open-Flow Microperfusion and Microdialysis Methodologies When Sampling Topically Applied Fentanyl and Benzoic Acid in Human Dermis Ex Vivo

Authors Holmgaard, Rikke; Benfeldt, E; Nielsen, J B; Gatschelhofer, C; Sorensen, J a; Höfferer, C; Bodenlenz, Manfred; Pieber, Thomas R; Sinner, F.

Health

2011

Absolute/relative bioavailability and metabolism of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (tetraenes) after intravenous and oral single doses to rats

Authors Ardjomand-Woelkart, Karin; Kollroser, Manfred; Magnes, Christoph; Sinner, Frank; Frye, Reginald F; Derendorf, Hartmut; Bauer, Rudolf; Butterweck, Veronika

Health

2011

The propeptide of yeast cathepsin D inhibits programmed necrosis

Authors Carmona-Gutiérrez, D; Bauer, M A; Ring, J; Knauer, H; Eisenberg, T; Büttner, S; Ruckenstuhl, C; Reisenbichler, A; Magnes, C; Rechberger, G N; Birner-Gruenberger, R; Jungwirth, H; Fröhlich, K-U; Sinner, F; Kroemer, G; Madeo, F

Health

2011

Prolonged depression-like behavior caused by immune challenge: influence of mouse strain and social environment

Authors Painsipp, Evelin; Köfer, Martin J.; Sinner, Frank; Holzer, Peter

Health

2011

Headspace-SPME-GC/MS as a simple cleanup tool for sensitive 2,6-diisopropylphenol analysis from lipid emulsions and adaptable to other matrices

Authors Pickl, Karin E; Adamek, Viktor; Gorges, Roland; Sinner, Frank M

Health

2011

The use of chitosan-6-mercaptonicotinic acid nanoparticles for oral peptide drug delivery

Authors Millotti, Gioconda; Perera, Glen; Vigl, Claudia; Pickl, Karin; Sinner, Frank Michael; Bernkop-Schnürch, Andreas

Health

2010

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

Authors Chandak, Prakash G.; Radović, Branislav; Aflaki, Elma; Kolb, Dagmar; Buchebner, Marlene; Fröhlich, Eleonore; Magnes, Christoph; Sinner, Frank; Haemmerle, Guenter; Zechner, Rudolf; Tabas, Ira; Levak-Frank, Sanja; Kratky, Dagmar

Health

2009

Induction of autophagy by spermidine promotes longevity

Authors Eisenberg, Tobias; Knauer, Heide; Schauer, Alexandra; Büttner, Sabrina; Ruckenstuhl, Christoph; Carmona-Gutierrez, Didac; Ring, Julia; Schroeder, Sabrina; Magnes, Christoph; Antonacci, Lucia; Fussi, Heike; Deszcz, Luiza; Hartl, Regina; Schraml, Elisabeth; Criollo, Alfredo; Megalou, Evgenia; Weiskopf, Daniela; Laun, Peter; Heeren, Gino; Breitenbach, Michael; Grubeck-Loebenstein, Beatrix; Herker, Eva; Fahrenkrog, Birthe; Fröhlich, Kai-Uwe; Sinner, Frank; Tavernarakis, Nektarios; Minois, Nadege; Kroemer, Guido; Madeo, Frank

Health

2009

Ring-opening metathesis polymerization for the preparation of norbornene-based weak cation-exchange monolithic capillary columns

Authors Gatschelhofer, Christina; Mautner, Agnes; Reiter, Franz; Pieber, Thomas R; Buchmeiser, Michael R; Sinner, Frank M

Health

2008

Insulin glulisine, insulin lispro and regular human insulin show comparable end-organ metabolic effects: an exploratory study

Authors Horvath, K; Bock, G; Regittnig, W; Bodenlenz, Manfred; Wutte, A; Plank, J; Magnes, Christoph; Sinner, F.; Fürst-Recktenwald, S.; Theobald, K; Pieber, Thomas R

Health

2008

Ring-opening metathesis polymerization-derived monolithic capillary columns for high-performance liquid chromatography. Downscaling and application in medical research

Authors Sinner, Frank M; Gatschelhofer, Christina; Mautner, Agnes; Magnes, Christoph; Buchmeiser, Michael R; Pieber, Thomas R

Health

2008

Validated comprehensive analytical method for quantification of coenzyme A activated compounds in biological tissues by online solid-phase extraction LC/MS/MS.

Authors Magnes, Christoph; Suppan, Maria; Pieber, Thomas R; Moustafa, Tarek; Trauner, Michael; Haemmerle, Guenter; Sinner, Frank M

Health

2007

Proportional Dose-Response Relationship and Lower Within-Patient Variability of Insulin Detemir and NPH Insulin in Subjects With Type 1 Diabetes Mellitus

Authors Wutte, A; Plank, J; Bodenlenz, Manfred; Magnes, Christoph; Regittnig, W; Sinner, F.; Rønn, B.; Zdravkovic, M; Pieber, T.

Health

2007

Rapid online-SPE-MS/MS method for ketoprofen determination in dermal interstitial fluid samples from rats obtained by microdialysis or open-flow microperfusion

Authors Pickl, Karin E.; Magnes, Christoph; Bodenlenz, Manfred; Pieber, Thomas R.; Sinner, Frank M.

Health

2007

Voltage-assisted capillary LC of peptides using monolithic capillary columns prepared by ring-opening metathesis polymerization

Authors Sedláková, Pavla; Miksik, Ivan; Gatschelhofer, Christina; Sinner, Frank M; Buchmeiser, Michael R

Health

2006

Enantioseparation of glycyl-dipeptides by CEC using particle-loaded monoliths prepared by ring-opening metathesis polymerization (ROMP)

Authors Gatschelhofer, Christina; Schmid, Martin G; Schreiner, Karin; Pieber, Thomas R; Sinner, Frank M; Gübitz, Gerald

Health

2006

Poly(cyclooctene)-based monolithic columns for capillary high performance liquid chromatography prepared via ring-opening metathesis polymerization

Authors Schlemmer, Bettina; Gatschelhofer, Christina; Pieber, Thomas R; Sinner, Frank M; Buchmeiser, Michael R

Health

2005

A Double-Blind, Randomized, Dose-Response Study Investigating the Pharmacodynamic and Pharmacokinetic Properties of the Long-Acting Insulin Analog Detemir

Authors Plank, Johannes; Bodenlenz, Manfred; Sinner, Frank; Magnes, Christoph; Görzer, Evelyn; Regittnig, Werner; Endahl, Lars A.; Draeger, Eberhard; Zdravkovic, Milan; Pieber, Thomas R

Health

2005

LC/MS/MS Method for Quantitative Determination of Long-Chain Fatty Acyl-CoAs

Authors Magnes, Christoph; Sinner, Frank M; Regittnig, Werner; Pieber, Thomas R

Health

2005

Evaluation of ring-opening metathesis polymerization (ROMP)-derived monolithic capillary high performance liquid chromatography columns

Authors Gatschelhofer, Christina; Magnes, Christoph; Pieber, Thomas R; Buchmeiser, Michael R; Sinner, Frank M

Health

2005

Measurement of interstitial insulin in human adipose and muscle tissue under moderate hyperinsulinemia by means of direct interstitial access

Authors Bodenlenz, Manfred; Schaupp, Lukas A; Druml, Tatjana; Sommer, Romana; Wutte, Andrea; Schaller, Helga C; Sinner, Frank; Wach, Paul; Pieber, Thomas R

Health

2000

Ring-Opening Metathesis Polymerization: Access to a New Class of Functionalized, Monolithic Stationary Phases for Liquid Chromatography

Authors Sinner, Frank Michael; Buchmeiser, Michael Rudolf

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JOANNEUM RESEARCH provides innovation and technology services in the field of applied research. As a research company working on behalf of various federal provinces and regions in Austria, our expertise shapes the development of our modern society and economy – sustainably, and always with a focus on people. As a multidisciplinary team working in a flexible set-up that fosters innovation, we always live up to the highest social and scientific standards.

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