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Diet-induced weight loss decreases adipose tissue oxygen tension with parallel changes in adipose tissue phenotype and insulin sensitivity in overweight humans

Beteiligte Autoren der JOANNEUM RESEARCH:
Autor*innen:
Vink, R. G.; Roumans, N. J.; Čajlaković, M.; Cleutjens, J. P. M.; Boekschoten, M. V.; Fazelzadeh, P.; Vogel, M. A. A.; Blaak, E. E.; Mariman, E. C.; van Baak, M. A.; Goossens, G. H.
Abstract:
Although adipose tissue (AT) hypoxia is present in rodent models of obesity, evidence for this in humans is limited. Here, we investigated the effects of diet-induced weight loss (WL) on abdominal subcutaneous AT oxygen tension (pO2), AT blood flow (ATBF), AT capillary density, AT morphology and transcriptome, systemic inflammatory markers and insulin sensitivity in humans.
Titel:
Diet-induced weight loss decreases adipose tissue oxygen tension with parallel changes in adipose tissue phenotype and insulin sensitivity in overweight humans
Seiten:
722–728
Publikationsdatum
2017

Publikationsreihe

Nummer
41
Beitrag
5
ISSN
1476-5497
Proceedings
International Journal of Obesity

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